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Does running water really trigger the urge to pee? Experts explain the brain-bladder connection

<p><em><a href="https://theconversation.com/profiles/james-overs-1458017">James Overs</a>, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a>; <a href="https://theconversation.com/profiles/david-homewood-1458022">David Homewood</a>, <a href="https://theconversation.com/institutions/melbourne-health-950">Melbourne Health</a>; <a href="https://theconversation.com/profiles/helen-elizabeth-oconnell-ao-1458226">Helen Elizabeth O'Connell AO</a>, <a href="https://theconversation.com/institutions/the-university-of-melbourne-722">The University of Melbourne</a>, and <a href="https://theconversation.com/profiles/simon-robert-knowles-706104">Simon Robert Knowles</a>, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a></em></p> <p>We all know that feeling when nature calls – but what’s far less understood is the psychology behind it. Why, for example, do we get the urge to pee just before getting into the shower, or when we’re swimming? What brings on those “nervous wees” right before a date?</p> <p>Research suggests our brain and bladder are in constant communication with each other via a neural network called the <a href="https://www.einj.org/journal/view.php?doi=10.5213/inj.2346036.018">brain-bladder axis</a>.</p> <p>This complex web of circuitry is comprised of sensory neural activity, including the sympathetic and parasympathetic nervous systems. These neural connections allow information to be sent <a href="https://doi.org/10.3390/diagnostics12123119">back and forth</a> between the brain and bladder.</p> <p>The brain-bladder axis not only facilitates the act of peeing, but is also responsible for telling us we need to go in the first place.</p> <h2>How do we know when we need to go?</h2> <p>As the bladder fills with urine and expands, this activates special receptors detecting stretch in the nerve-rich lining of the bladder wall. This information is then relayed to the “periaqueductal gray” – a part of the brain in the brainstem which <a href="https://www.nature.com/articles/nrn2401">constantly monitors</a> the bladder’s filling status.</p> <figure class="align-center zoomable"><a href="https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=1000&amp;fit=clip"><img src="https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px" srcset="https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=600&amp;h=454&amp;fit=crop&amp;dpr=1 600w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=30&amp;auto=format&amp;w=600&amp;h=454&amp;fit=crop&amp;dpr=2 1200w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=15&amp;auto=format&amp;w=600&amp;h=454&amp;fit=crop&amp;dpr=3 1800w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;h=570&amp;fit=crop&amp;dpr=1 754w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=30&amp;auto=format&amp;w=754&amp;h=570&amp;fit=crop&amp;dpr=2 1508w, https://images.theconversation.com/files/547931/original/file-20230913-19-2kgkhk.jpg?ixlib=rb-1.1.0&amp;q=15&amp;auto=format&amp;w=754&amp;h=570&amp;fit=crop&amp;dpr=3 2262w" alt="" /></a><figcaption><span class="caption">The periaqueductal gray is a section of gray matter located in the midbrain section of the brainstem.</span> <span class="attribution"><a class="source" href="https://en.wikipedia.org/wiki/Brainstem#/media/File:1311_Brain_Stem.jpg">Wikimedia/OpenStax</a>, <a class="license" href="http://creativecommons.org/licenses/by-sa/4.0/">CC BY-SA</a></span></figcaption></figure> <p>Once the bladder reaches a certain threshold (roughly 250-300ml of urine), another part of the brain called the “pontine micturition centre” is activated and signals that the bladder needs to be emptied. We, in turn, <a href="https://pubmed.ncbi.nlm.nih.gov/16254993/">register this</a> as that all-too-familiar feeling of fullness and pressure down below.</p> <p>Beyond this, however, a range of situations can trigger or exacerbate our need to pee, by increasing the production of urine and/or stimulating reflexes in the bladder.</p> <h2>Peeing in the shower</h2> <p>If you’ve ever felt the need to pee while in the shower (no judgement here) it may be due to the sight and sound of running water.</p> <p>In a 2015 study, <a href="https://doi.org/10.1371/journal.pone.0126798">researchers demonstrated</a> that males with urinary difficulties found it easier to initiate peeing when listening to the sound of running water being played on a smartphone.</p> <p>Symptoms of overactive bladder, including urgency (a sudden need to pee), have also been <a href="https://www.alliedacademies.org/articles/environmental-cues-to-urgency-and-incontinence-episodes-in-chinesepatients-with-overactive-urinary-bladder-syndrome.html">linked to</a> a range of environmental cues involving running water, including washing your hands and taking a shower.</p> <p>This is likely due to both physiology and psychology. Firstly, the sound of running water may have a relaxing <em>physiological</em> effect, increasing activity of the parasympathetic nervous system. This would relax the bladder muscles and prepare the bladder for emptying.</p> <p>At the same time, the sound of running water may also have a conditioned <em>psychological</em> effect. Due to the countless times in our lives where this sound has coincided with the actual act of peeing, it may trigger an instinctive reaction in us to urinate.</p> <p>This would happen in the same way <a href="https://www.simplypsychology.org/pavlov.html">Pavlov’s dog learnt</a>, through repeated pairing, to salivate when a bell was rung.</p> <h2>Cheeky wee in the sea</h2> <p>But it’s not just the sight or sound of running water that makes us want to pee. Immersion in cold water has been shown to cause a “cold shock response”, <a href="https://pubmed.ncbi.nlm.nih.gov/19945970">which activates</a> the sympathetic nervous system.</p> <p>This so-called “fight or flight” response drives up our blood pressure which, in turn, causes our kidneys to filter out more fluid from the bloodstream to stabilise our blood pressure, in a process called “<a href="https://link.springer.com/article/10.1007/BF00864230">immersion diuresis</a>”. When this happens, our bladder fills up faster than normal, triggering the urge to pee.</p> <p>Interestingly, immersion in very warm water (such as a relaxing bath) may also increase urine production. In this case, however, it’s due to activation of the parasympathetic nervous system. <a href="https://doi.org/10.1007/s004210050065">One study</a> demonstrated an increase in water temperature from 40℃ to 50℃ reduced the time it took for participants to start urinating.</p> <p>Similar to the effect of hearing running water, the authors of the study suggest being in warm water is calming for the body and activates the parasympathetic nervous system. This activation can result in the relaxation of the bladder and possibly the pelvic floor muscles, bringing on the urge to pee.</p> <h2>The nervous wee</h2> <p>We know stress and anxiety can cause bouts of nausea and butterflies in the tummy, but what about the bladder? Why do we feel a sudden and frequent urge to urinate at times of heightened stress, such as before a date or job interview?</p> <p>When a person becomes stressed or anxious, the body goes into fight-or-flight mode through the activation of the sympathetic nervous system. This triggers a cascade of physiological changes designed to prepare the body to face a perceived threat.</p> <p>As part of this response, the muscles surrounding the bladder may contract, leading to a more urgent and frequent need to pee. Also, as is the case during immersion diuresis, the increase in blood pressure associated with the stress response may <a href="https://doi.org/10.1172/JCI102496">stimulate</a> the kidneys to produce more urine.</p> <h2>Some final thoughts</h2> <p>We all pee (most of us several times a day). Yet <a href="https://doi.org/10.5489/cuaj.1150">research has shown</a> about 75% of adults know little about how this process actually works – and even less about the brain-bladdder axis and its role in urination.</p> <p><a href="https://www.continence.org.au/about-us/our-work/key-statistics-incontinence#:%7E:text=Urinary%20incontinence%20affects%20up%20to,38%25%20of%20Australian%20women1.">Most Australians</a> will experience urinary difficulties at some point in their lives, so if you ever have concerns about your urinary health, it’s extremely important to consult a healthcare professional.</p> <p>And should you ever find yourself unable to pee, perhaps the sight or sound of running water, a relaxing bath or a nice swim will help with getting that stream to flow.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/210808/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><a href="https://theconversation.com/profiles/james-overs-1458017"><em>James Overs</em></a><em>, Research Assistant, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a>; <a href="https://theconversation.com/profiles/david-homewood-1458022">David Homewood</a>, Urology Research Registrar, Western Health, <a href="https://theconversation.com/institutions/melbourne-health-950">Melbourne Health</a>; <a href="https://theconversation.com/profiles/helen-elizabeth-oconnell-ao-1458226">Helen Elizabeth O'Connell AO</a>, Professor, University of Melbourne, Department of Surgery. President Urological Society Australia and New Zealand, <a href="https://theconversation.com/institutions/the-university-of-melbourne-722">The University of Melbourne</a>, and <a href="https://theconversation.com/profiles/simon-robert-knowles-706104">Simon Robert Knowles</a>, Associate Professor and Clinical Psychologist, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/does-running-water-really-trigger-the-urge-to-pee-experts-explain-the-brain-bladder-connection-210808">original article</a>.</em></p>

Mind

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Pee-wee Herman actor dies after secret health battle

<p>The world is mourning the passing of Paul Reubens, the actor whose infectious humour as Pee-wee Herman brought smiles to millions. He has left us at the age of 70 after a prolonged and entirely secret battle with cancer.</p> <p><span style="font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', 'Helvetica Neue', sans-serif;">A somber statement on his official Instagram account read, "Last night we said farewell to Paul Reubens, an iconic American actor, comedian, writer, and producer whose beloved character Pee-wee Herman delighted generations of children and adults with his positivity, whimsy, and belief in the importance of kindness."</span></p> <p>His battle with cancer finally took him away from us, a fact that he had been fighting privately and courageously for years.</p> <p>"Paul bravely and privately fought cancer for years with his trademark tenacity and wit," the tribute continued. "A gifted and prolific talent, he will forever live in the comedy pantheon and in our hearts as a treasured friend and man of remarkable character and generosity of spirit."</p> <p>Paul Reubens' journey began in the 1970s as an improv comedian and stage actor with the Groundlings troupe in Los Angeles. The character of Pee-wee Herman was born at The Groundlings Theatre in February 1981 and went on to become a sensation through the 1985 film <em>Pee-wee’s Big Adventure</em>.</p> <p>The subversive 1986 to 1990 Emmy-winning TV series <em>Pee-wee’s Playhouse</em> further solidified his status as a comedic icon, and he revisited the endearing Pee-wee character on various occasions over the years, including the 2016 Netflix movie <em>Pee-wee’s Big Holiday</em>.</p> <p>In 2010, he brought Pee-wee to life on a live Broadway stage in <em>The Pee-wee Herman Show</em>, which garnered a Primetime Emmy Award nomination for Outstanding Variety, Music, or Comedy Special.</p> <p>Beyond Pee-wee, Paul Reubens showcased his acting versatility with roles on TV shows like DC’s <em>Legends of Tomorrow</em>, <em>Gotham</em>, and <em>The Blacklist</em>.</p> <p>Amidst it all, there was a poignant revelation that Reubens had been considered for the iconic character of <em>Roger Rabbit</em>. Footage from the early 1980s surfaced, showing him voicing the role in an early version of <em>Who Framed Roger Rabbit?</em></p> <p>In his final message to his fans, Reubens conveyed: "Please accept my apology for not going public with what I’ve been facing the last six years. I have always felt a huge amount of love and respect from my friends, fans, and supporters. I have loved you all so much and enjoyed making art for you."</p> <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-captioned="" data-instgrm-permalink="https://www.instagram.com/p/CvXme4ZxAR0/?utm_source=ig_embed&amp;utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/p/CvXme4ZxAR0/?utm_source=ig_embed&amp;utm_campaign=loading" target="_blank" rel="noopener">A post shared by Pee-wee Herman (@peeweeherman)</a></p> </div> </blockquote> <p>In a gesture of love for his late parents, Judy and Milton Rubenfeld, Paul Reubens requested that any donations in his honour be made to Stand Up to Cancer or other organisations supporting dementia and Alzheimer’s.</p> <p><em>Images: Instagram</em></p>

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Food can play a part of the colour of your poo and pee

<h1>Optimal pee and poo colour for your health</h1> <h2>Food, medications and illnesses can all play a part.</h2> <div class="copy"> <p>Out of the blue I passed bright red pee. I freaked, thinking it was a sign of terminal disease. Then I remembered the roasted beetroot tarts served at the party the night before – so delicious I’d eaten three!</p> <p>Beetroot, artificial colours, vitamin supplements and medications can change the colour of your urine or bowel motions. Knowing which colour changes are due to food or medicines can save you worry, or provide an early alert to get to the doctor.</p> <h2>Beeturia</h2> <p>Beeturia is the term for passing red urine after eating beetroot. The red colour comes from a pigment called betalain, also in some flower petals, fruit, leaves, stems and roots. Concentrated beetroot extract, called Beet Red or additive number 162 on food labels, can be added to “pink” foods, such as ice-cream.</p> <p>Whether betalain turns your pee red or not depends on the type of beetroot, amount eaten and how it’s prepared, because betalain is destroyed by heat, light and acid.</p> <p>How much betalain enters your digestive tract depends on stomach acid and stomach emptying rate (people taking medications to reduce stomach acid may be prone to beeturia). Once in the blood stream, betalain pigments are filtered out by the kidneys. Most is eliminated two to eight hours after eating.</p> <p>Persistent red urine can be due to blood loss, infection, enlarged prostate, cancer, cysts, kidney stones or after a long-distance run. If you see red and have not been eating beetroot, see your doctor.</p> <h2>What should your pee look like?</h2> <p>Normal pee should be the colour of straw. If your pee is so colourless that it looks like water, you probably drank more than you needed.</p> <p>Very dark yellow pee usually means you are a bit dehydrated and need to drink more water.</p> <p>Compare your pee colour to the Cleveland Clinic’s scale below.</p> <span class="attribution"><span class="source">Courtesy Cleveland Clinic</span></span> <h2>Strange pee colours due to food, drugs or disease</h2> <p>Pee the colour of syrup or molasses needs medical investigation. While it could be due to extreme dehydration, it can be a sign of liver diseases such as hepatitis and cirrhosis, where a build up of bilirubin spills into your pee. Bilirubin is a breakdown product of red blood cells; it’s also responsible for poo’s normal brown colour.</p> <p>Pee can turn bright orange or yellow when taking beta-carotene or vitamin B supplements, especially large doses of riboflavin (vitamin B2). These supplements are water soluble. What your body can’t use or store gets filtered out via your kidneys and into pee.</p> <p>Medications including phenazopyridine (for urinary tract infections), rifampin (antibiotic for treating tuberculosis and Legionnaire’s disease), warfarin (blood thinner) and some laxatives can also change pee colour.</p> <p>If you pass blue or green pee, it’s most likely due to food colouring or methylene blue used in some diagnostic test procedures and some drugs.</p> <p>But a range of medications can also trigger blue or green urine. These include antihistamines, anti-inflammatories, antibacterials, antidepressants, some nausea drugs or those for reducing stomach acid.</p> <p>Rare genetic conditions Hartnup disease and Blue diaper syndrome cause blue-green urine. So see your doctor if it persists or it happens in an infant.</p> <p>You should never see purple pee, but hospital staff might. “Purple urine bag” syndrome happens in patients with catheters and infections or complications. The catheter or bag turns purple due to a chemical reaction between protein breakdown products in urine and the plastic.</p> <p>Occasionally, pee can be frothy. It’s a normal reaction if protein intake is high and pee comes out fast. It is more likely if you consume protein powders or protein supplements. Excess protein can’t be stored in the body so the nitrogen component (responsible for the froth) gets removed and the kidneys excrete it as urea.</p> <p>See your doctor if the frothiness doesn’t go away or gets worse, as protein can leak into pee if you have kidney disease.</p> <h2>Poo colours of the rainbow</h2> <p>Normal poo colour ranges from light yellow to brown to black. The colour is due to a mix of bile, which starts off green in the gall bladder, and bilirubin a yellow breakdown product from red blood cells.</p> <p>Poo can turn green after consuming food and drink containing blue or green food colouring, or if food travels too fast through the gut and some bile is still present.</p> <p>Poo that is yellow, greasy and smells really bad signals food malabsorption. If this colour is associated with weight loss in an adult or poor growth in a child, see a doctor to rule out gut infections such as giardia or medical conditions like coeliac disease.</p> <p>Very pale or clay-coloured poo can happen when taking some anti-diarrhoeal medications, or when digestive problems affect the liver, gut, pancreas or gall bladder.</p> <p>At the other extreme of the colour spectrum, black poo could be a serious medical issue due to bleeding in the stomach or upper gut. Or it could be a harmless side-effect from taking iron supplements, or eating lots of licorice.</p> <p>Red poo can also be a serious medical issue due to bleeding in the lower gut, or from haemorrhoids, or harmless after having large amounts of red food colouring.</p> <p>If you don’t know what colour your pee or poo is, take a look. If you see a colour that’s out of the ordinary and you haven’t eaten anything unusual, take a picture and make an appointment to show your GP.</p> <p>Clare Collins, Professor in Nutrition and Dietetics, <em>University of Newcastle</em>; Kristine Pezdirc, Research Associate | Post-doctoral Researcher, <em>University of Newcastle</em>, and Megan Rollo, Postdoctoral Research Fellow, Nutrition &amp; Dietetics, <em>University of Newcastle</em></p> <!-- Start of tracking content syndication. Please do not remove this section as it allows us to keep track of republished articles --> <img id="cosmos-post-tracker" style="opacity: 0; height: 1px!important; width: 1px!important; border: 0!important; position: absolute!important; z-index: -1!important;" src="https://syndication.cosmosmagazine.com/?id=11561&amp;title=Optimal+pee+and+poo+colour+for+your+health" alt="" width="1" height="1" /> <!-- End of tracking content syndication --></div> <div id="contributors"> <p>This article was originally published on Cosmos Magazine and was written by The Conversation. The Conversation is an independent, not-for-profit media outlet that uses content sourced from the academic and research community.</p> </div>

Food & Wine