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"I want answers": Simon Dorante-Day's cunning plan to prove royal connections

<p>The Queensland man claiming to be the son of King Charles and Queen Camilla has shared his new plan to prove once and for all that he has royal family connections. </p> <p>Simon Dorante-Day has long claimed through his 30 years of research, he discovered that he is the illegitimate son of the monarch, and has attempted to prove his theory through various means. </p> <p>Now, his new plan to get his hands on royal DNA to unequivocally prove his family heritage involves another member of the royal family. </p> <p>Speaking with <a href="https://7news.com.au/lifestyle/aussie-man-claiming-to-be-charles-son-drops-new-prince-harry-dna-bombshell-c-13488374" target="_blank" rel="noopener"><em>7News</em></a>, the 57-year-old said he and his wife have been told by a “trusted source” that Prince Harry could be amenable to helping them gather proof.</p> <p>“We got advice from a really good, really trusted source that we should approach Harry and make a connection there and ask for DNA,” Elvianna said.</p> <p>Simon added, “I was really taken aback when he said that. But it’s definitely something I’m going to do. I’ve long been a supporter of Harry and Meghan, I think it’s disgraceful the way they’ve been treated by the royal family."</p> <p>“The way they are treated on social media too, it’s just one big ‘Punch-Meghan-and-Harry-a-thon’, seriously. It’s really starting to annoy me."</p> <p>He said he is planning to "make contact with him and explore this as an opportunity," pointing out that the royal family's treatment of Harry could make him more willing to help.</p> <p>"At the end of the day, I feel like he just might be as keen as I am to expose what Charles and Camilla and the powers that be have done to me. The injustice."</p> <p>“It’s worth me pointing out that Charles and Camilla, Buckingham Palace, the entire royal family - not one of them has ever said my claims are not true. They’ve never denied what I believe, told me I’m wrong."</p> <p>Simon said “the wheels are in motion” in terms of making contact with Prince Harry, and that he’s hopeful of a positive outcome.</p> <p>“I want answers,” he said. “And I feel Prince Harry is the man to help me find them.”</p> <p>“And I think their silence speaks volumes.”</p> <p>Simon said “the wheels are in motion” in terms of making contact with Prince Harry, and that he’s hopeful of a positive outcome.</p> <p>“I want answers,” he said. “And I feel Prince Harry is the man to help me find them.”</p> <p><em>Image credits: Facebook / Getty Images </em></p>

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He's back! Charles and Camilla's secret "son" drops DNA bombshell

<p>The Australian man who has long claimed to be the secret child of King Charles and Queen Camilla has shared the details of a wild plot to extract his DNA. </p> <p>The 57-year-old man from Queensland revealed he was tracked down by an American woman, who claimed she was the illegitimate child of the late Prince Philip, and attempted to get a DNA sample from the man. </p> <p>Simon Dorante-Day has made headline around the world with his claims that he is the son of Charles and Camilla, which he says are the results of decades worth of research. </p> <p>“My grandmother, who had worked for the Queen, told me outright that I was Camilla and Charles’ son many times,” he said.</p> <p>Now, in an interview with <a href="https://7news.com.au/lifestyle/aussie-man-who-claims-to-be-charles-and-camillas-son-drops-biggest-ever-dna-bombshell-c-12788618" target="_blank" rel="noopener"><em>7News</em></a>, Dorante-Day shared the story of how he was tracked down by the American woman, who knocked on his door in the early hours of the morning on December 2nd. </p> <p>The 57-year-old and his wife Elvianna were immediately skeptical of the woman, who said she used a private investigator to track him down. </p> <p>“This woman claimed that she was the secret illegitimate daughter of Prince Philip who lived in San Francisco,” Dorante-Day said.</p> <p>“She explained that she had travelled from the US after hiring an investigator to track me down in Queensland. The whole purpose of her visit was to ask me for a sample of my DNA."</p> <p>“She wanted to compare it to hers, to basically prove that we were both related to the royal family.”</p> <p>After humouring the woman and letting her share her evidence along with her elaborate story, Simon concluded that the whole thing was a scam, along with an illegal attempt to extract his DNA.</p> <p>“This woman had a lot of so-called proof to back up her claims, but the whole thing just seemed really fishy,” he said.</p> <p>He recalled how the woman shared her own adoption story, which resulted in her turning to the FBI for help, who allegedly handed her her original birth certificate, which listed Prince Philip as her father. </p> <p>“Of course my bulls*** meter is flying off the handle at this point. I know how hard it is to get any government authority to address these sorts of issues — I hardly think the Federal Bereau of Investigation would just offer up the fact that she was the daughter of the Queen’s late husband," Simon said. </p> <p>“It was all just wild.”</p> <p>The Queensland father and grandfather said it wasn’t long until the woman gave away her real reason for wanting his DNA: money.</p> <p>“She said that she’s already been given a large payout from the royal family after she proved she was the daughter of Prince Philip,” he said.</p> <p>“And she felt that if she was able to compare my DNA to her DNA, and prove we were both descendants of the royal family, then we could ask them for even more money."</p> <p>“Elvianna and I told her what we’ve said to everyone from day one — this isn’t about money for us, at all. This is about us finding out who my birth parents are and protecting my family. We have never wanted money.”</p> <p>After saying goodbye to the pair, Dorante-Day said he and his wife were left reeling.</p> <div> <p>“At the end of the day, this was an illegal attempt to procure my DNA,” he said. </p> <p>Despite the whole experience leaving Dorante-Day and his wife rattled, he said his stance on proving that he is Charles and Camilla's son has not changed. </p> <p>“It takes a lot of work, money and time to build a case like this, but I am confident I will get there,” he said.</p> <p>“I know Charles and Camilla are my parents and I’m ready to prove it.”</p> <p><em>Image credits: Supplied</em></p> </div>

Family & Pets

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‘He was horrific!’: Nearly two thirds of family historians are distressed by what they find – should DNA kits come with warnings?

<p><em><a href="https://theconversation.com/profiles/susan-moore-1446031">Susan Moore</a>, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a></em></p> <p>In 1853, my great great grandmother Charlotte died giving birth to her 13th child, in a tent on the banks of the Yarra River in what is now South Melbourne – but was then an overcrowded, muddy hellhole known as <a href="https://blogs.slv.vic.gov.au/our-stories/canvas-town-a-floating-city-devoured-by-the-sun/">Canvas Town</a>. The baby, William, died shortly afterwards. Researching Charlotte’s story made me both sad for her loss and angry at the powerlessness of women’s lives then.</p> <p>I’m not the only one to have experienced intense emotions – both negative and positive – while researching my forebears.</p> <p>On Facebook pages, in <a href="https://time.com/5492642/dna-test-results-family-secret-biological-father/">media stories</a> and <a href="https://www.sbs.com.au/ondemand/tv-series/who-do-you-think-you-are">on TV</a>, you’ll find a flood of hobby genealogists discovering shocking things about their ancestors – or even their own identity.</p> <p>My recent research revealed about two thirds of family historians have experienced <a href="https://www.mdpi.com/2313-5778/7/2/26">strong negative emotions</a> like sorrow or anger through their hobby.</p> <p>And nearly all respondents had experienced strong positive emotions such as joy or pride.</p> <h2>Passionate ‘kin keepers’</h2> <p>In 2019, Doreen Rosenthal and I surveyed 775 Australian hobbyist family historians to examine their <a href="https://www.routledge.com/The-Psychology-of-Family-History-Exploring-Our-Genealogy/Moore-Rosenthal-Robinson/p/book/9780367820428">motivations</a>.</p> <p>They were adults aged between 21 and 93, but most were older and the median age was 63. The majority (85%) were women. This seems to be typical of hobbyist family historians. Women often take on the role of “kin keeper” – and have the time to devote to it when they’ve finished rearing children and have retired from paid work.</p> <p>Survey respondents described why they were passionately engaged with their hobby – and how it made them feel. Some 48% “sometimes” felt strong negative emotions about what they found, while 15% did “often”.</p> <p>There were five common distress triggers.</p> <h2>1. Ancestors behaving badly</h2> <p>The first and most common distress trigger was the discovery of ancestors who had behaved badly – either as individuals, or by profiting from unjust social conditions. Finding these forebears made family historians feel confronted, shocked and sometimes ashamed.</p> <p>They said things like: "[The worst thing was] finding the bigamist! He was horrific!! Very confronting thinking that I have some of his blood in my veins!"</p> <p>And: "[It was] difficult finding that ancestors may have been involved in unsavoury behaviours or events. The problem is trying to understand the context of how they were able to do things that are socially and legally unacceptable today and not things I can be proud of."</p> <h2>2. Ancestors treated cruelly</h2> <p>It was also distressing to discover ancestors who had been cruelly treated. This elicited disturbing, even “heartbreaking” feelings – and, at least implicitly, indignation at injustice. Many were deeply moved by what their ancestors experienced.</p> <p>As one survey respondent put it: "What is unexpected is the relationships that can be formed with those who are no longer with us. That I can be moved by the plight of my paternal step great great grandmother who was incarcerated in a mental institution from 1913 to 1948 without review, without visitors, to get her out of the way."</p> <h2>3. Sad stories</h2> <p>Sadness was often specifically mentioned. As in the case of my great great grandmother who died in childbirth, sadness was usually a response to the hardships and tragedies ancestors faced in more challenging times.</p> <p>Women commonly did not survive childbirth, neonatal deaths were frequent, people died of diseases medical science has now conquered. Poverty was rife and war a constant threat.</p> <p>"[It was difficult] discovering the tragedies encountered by my Irish ancestors who came to Australia and their struggles and heartbreaking stories of survival for the next three generations."</p> <p>"[It is distressing] to uncover particularly sad and desperate times in some ancestors’ lives. For example, a destitute widow who admitted her child to an orphan asylum for three years, only to have her child die of typhoid fever within two weeks of returning home."</p> <h2>4. Family secrets and betrayal</h2> <p>The fourth distress trigger was a belief by the family history researcher that they had been betrayed by other family members: through secrets, lies and feeling their lived experience was ignored or denied.</p> <p>This is particularly likely for those who discover “secrets” about their parentage – for example, the late-life discovery of adoption, parental infidelity or previously unknown siblings.</p> <p>Trust is damaged. If family members can lie about these important things, what else might they lie about?</p> <p>As one woman commented: "My mother’s half-sister did not accept that she shared a father with my mother. My great grandmother lied about who my grandfather’s father was. My great great grandmother also lied. All these lies were very distressing."</p> <h2>5. Moral dilemmas</h2> <p>Finally, several respondents expressed doubt and confusion at the moral dilemmas they faced on discovering information that could greatly distress other living relatives. Should they tell or not?</p> <p>An emotional burden attaches to withholding potentially distressing information of this kind. Yet there is also guilt and fear about the possible outcomes of sharing it.</p> <p>"I knew an aunt had an illegitimate child before she married. Through DNA I found her granddaughter. I have yet to inform this girl who she is. I don’t feel it’s my right as she has absolutely no idea of any adoption of her father."</p> <p>"A really distressing find was that my great aunt’s husband had committed a terrible murder. I have not been able to speak about this with the descendants of the couple."</p> <h2>Healthy outcomes from bad feelings</h2> <p>Sometimes these distressing feelings can promote healthy, growth-enhancing outcomes. After the initial shock, some traumatic genealogical discoveries lead to a greater understanding of the past and its influence.</p> <p>Placing ancestors’ maladaptive or distressing behaviours, or their misfortunes, into historical and social context can help with acceptance and forgiveness, and stimulate emotional healing and personal growth.</p> <p>Initial feelings of distress about past injustices and tragedies are sometimes replaced by admiration for the strength and resilience of one’s forebears. This can positively influence personal wellbeing and resilience.</p> <h2>How can family and professionals help?</h2> <p>I processed my great great grandmother’s story by writing it down and sharing it with family members. We reworked our sadness at her fate into a positive family narrative, emphasising her bravery and the strengths her surviving children showed.</p> <p>Support can mean just disclosing these stories to family members, friends and other family historians. But for some, it may be helpful to discuss these topics privately with a counsellor or therapist, especially if they’ve led to a breakdown in family relationships or an assault on one’s sense of identity.</p> <p>Counsellors and psychologists should develop strategies to support clients distressed by genealogical findings – and encourage them to use their new knowledge for personal growth and greater understanding of family dynamics.</p> <p>Should providers of genealogical research products (especially DNA tests) educate their customers about their products’ potential to cause distress?</p> <p>Trigger warnings might be overkill. But they could issue lists of support resources for those who are upset or disoriented by their findings.</p> <p>As more people gain access to more genealogical data – with the potential to challenge identity and uncover family secrets – it’s worth thinking about.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/207430/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /></p> <p><em><a href="https://theconversation.com/profiles/susan-moore-1446031">Susan Moore</a>, Emeritus Professor, Faculty of Health, Arts and Design, <a href="https://theconversation.com/institutions/swinburne-university-of-technology-767">Swinburne University of Technology</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/he-was-horrific-nearly-two-thirds-of-family-historians-are-distressed-by-what-they-find-should-dna-kits-come-with-warnings-207430">original article</a>.</em></p>

Family & Pets

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Madeleine McCann's parents speak out after DNA test results

<p>Madeleine McCann's parents have spoken out after the results of Julia Faustyna's DNA test have returned. </p> <p>Julia Faustyna, a 21-year-old Polish woman, has been claiming to be the missing British child in a high-profile campaign that has seen her undergo a DNA test to prove her identity.</p> <p>The DNA results determined that Julia is not Maddie, despite Julia's claims of having similar facial features, suffering an abusive childhood and had starting to question her parentage as a result. </p> <p>Private detective Dr Fia Johansson arranged for Julia to give samples in the US for extensive DNA tests - including a DNA test similar to a 23andMe test, which established she is not Madeleine.</p> <p>The test looked into her heritage, and showed that she is from Poland, with some Lithuanian and Romanian heritage, <a href="https://www.thesun.co.uk/news/21808585/who-julia-wendell-madeleine-mccann/" target="_blank" rel="noopener"><em>The Sun</em></a> reported, but nothing to suggest any link to the McCann's. </p> <p>In response, a spokesman for Madeleine’s parents Kate and Gerry McCann said, “There isn’t anything to report at this time. If and when there is, it will come from The Metropolitan Police.”</p> <p>Julia is also facing a nervous wait for the results of further health tests as doctors fear she <a href="https://oversixty.co.nz/news/news/sad-health-news-for-woman-claiming-to-be-madeleine-mccann" target="_blank" rel="noopener">may have leukaemia</a>, Dr Johansson - with Julia’s permission - revealed to <em>The Sun</em>.</p> <p>She said, “Her health is very poor she has bad asthma and she suffers lots of pain in her bones."</p> <p>“She is booked in for a CT and MRI scan because of the pain in her bones."</p> <p>“Her blood work is also abnormal so my doctor here in the US is investigating whether she could have leukaemia so we are awaiting the results of that."</p> <p>“And if she needs any treatment we will make sure she gets that.”</p> <p><em>Image credits: Getty Images</em></p>

News

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Historic Swedish sailing ship slow to give up its secrets

<div> <p>The Swedish ship Vasa was supposed to be a beacon of military might when it launched in 1628, but it sank after sailing just over a kilometre, killing roughly 30 people  in the process.</p> <p>Since its recovery in 1961, the ship, its contents and the people who perished with it have become a valuable insight into 17th-century Swedish life.</p> <p>Now, an international team of researchers has looked closer at one of the skeletons, referred to as G, and have confirmed that it’s female.</p> <p>“Through osteological analysis it has been possible to discover a great deal about these people, such as their age, height and medical history. Osteologists recently suspected that G could be female, on the basis of the pelvis. DNA analysis can reveal even more,” says Dr Fred Hocker, director of research at the Vasa Museum, Sweden.</p> <div><a href="https://cosmosmagazine.com/science/biology/shipwrecks-habitats-microbiomes/"> </a></div> <p>“It is very difficult to extract DNA from bone which has been on the bottom of the sea for 333 years, but not impossible”, says Professor Marie Allen, a forensic geneticist at Uppsala University in Sweden.</p> <p>“Already some years ago we had indications that skeleton G was not a man but a woman. Simply put, we found no Y-chromosomes in G’s genetic material. But we could not be certain and wanted to confirm the result.”</p> <p>They were able to do that with a technique developed by the US Department of Defense’s Armed Forces Medical Examiner System’s Armed Forces DNA Identification Laboratory (AFMES-AFDIL).</p> <p>“We took new samples from bones for which we had specific questions. AFMES-AFDIL has now analysed the samples, and we have been able to confirm that G was a woman, thanks to the new test,” says Allen.</p> <p>Allen, along with AFMES-AFDIL collaborator Dr Kimberly Andreaggi, is now investigating the DNA for more detail about G.</p> <p>“Today we can extract much more information from historic DNA than we could earlier and methods are being continuously refined. We can say if a person was predisposed to certain illnesses, or even very small details, such as if they had freckles and wet or dry ear wax,” says Allen.</p> <p>The Vasa Museum, meanwhile, is collecting information for a book about the people who died on the ship.</p> <p>“We want to come as close to these people as we can. We have known that there were women on board Vasa when it sank, and now we have received confirmation that they are among the remains,” says museum historian Dr Anna Maria Forssberg.</p> <p>“I am currently researching the wives of seamen, so for me this is especially exciting, since they are often forgotten even though they played an important role for the navy.”</p> </div> <div id="contributors"> <p><em>This article was originally published on <a href="https://cosmosmagazine.com/history/vasa-shipwreck-female/" target="_blank" rel="noopener">cosmosmagazine.com</a> and was written by Ellen Phiddian. </em></p> <p><em>Images: Getty</em></p> </div>

Technology

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Julia Faustyna takes DNA test to prove wild identity claims

<p>Julia Faustyna, the Polish woman who is convinced she is the missing Madeleine McCann, has reportedly taken a DNA test to prove her claim.</p> <p>However, in a stunning twist to the tale, Faustyna’s private investigation with spokesperson Dr Fia Johansson has led the young woman to consider the possibility that she may actually be another missing child - Livia Schepp, who went missing with her twin sister in Switzerland in 2011. </p> <p>“I’ve spoken to her about this and she is open to the fact she could be any missing child out there,” Dr Johansson said while speaking to <em>The Sun</em>. “Not just Madeleine. Julia wants to know the truth about who she is.” </p> <p>While Faustyna’s main argument has involved the physical similarities between herself and Madeleine McCann, one of the pivotal points in her story is how she recognised a suspect from McCann’s case - a man she has named as her own abuser. </p> <p>“One of the reasons she made the connection to Madeleine is because one of the suspects in Madeleine’s case looks very much like a man who she says abused her as a child,” Dr Johansson explained. “But the same man could be connected to Madeleine and other missing children, this is how predators and traffickers work.”</p> <p>“Julia has taken a DNA test,” she confirmed, “and we are investigating if it’s possible to check her DNA with that of [the] missing Livia. We are investigating all possibilities at this stage.” </p> <p>Livia Schepp - and her twin sister Alessia - went missing when they were six, after their father abducted them from Switzerland in 2011. Days later, he took his own life in Italy, and when police discovered the body, the twins were nowhere to be seen. </p> <p>Faustyna, who claims to have post-traumatic amnesia due to sexual abuse in her childhood, lacks clear recollection of her formative years, and has stated while she can recall holidays, she doesn’t “recall my mother being there, for example, or my stepfather, much less my dad.”</p> <p>Whether or not any of Faustyna’s theories are true, the public will have to keep speculating, as no results have yet been shared. </p> <p>However, Faustyna’s viral “@iammadeleinemccan”, where she was sharing updates and side-by-side comparisons with her followers, has since been deleted from the platform. </p> <p>The removal coincides with reports of the DNA test, and after Faustyna closed both her Facebook and Tiktok accounts, disputing her parent’s claim that she was only in this for attention when she said “if you don’t like me, please unfollow. I don’t want fans or followers.”</p> <p><em>Images: Instagram, Twitter</em></p>

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“Loving grandfather” ousted as serial rapist

<p dir="ltr">A local Bondi grandfather has been ousted by police as a serial rapist - one of the worst in New South Wales.</p> <p dir="ltr">Following a long 40 years of investigations and using new technology for DNA as well as a shocking 12 crime scenes, Keith “Maggo” Simms has been identified as a serial rapist.</p> <p dir="ltr">Dubbed “The Beast of Bondi”, Simms is believed to have raped and terrorised more than 30 women in Sydney's eastern suburbs from 1986 to 2001.</p> <p dir="ltr">He died earlier this year on February 20 at the age of 66.</p> <p dir="ltr">When Simms was ready to attack a woman, he would wear a balaclava and approach them with a knife, putting a hand across their mouth and threatening to kill them.</p> <p dir="ltr">It was only in 2016, when police received a weak DNA match to a relative of Simms, that they were eventually able to tie the crimes back to him.</p> <p dir="ltr">Unfortunately for his victims, Simms died before police were able to question him and get them some form of justice.</p> <p dir="ltr">His family also had no idea and referred to him as a “loving family man”, and when his wife found out she was shocked.</p> <p dir="ltr">“His family had no idea at all … we met with his wife and she was absolutely shocked,” Detective Sergeant Shelley Johns, from Strike Force Doreen said, The Daily Telegraph reported.</p> <p dir="ltr">Sex Crimes squad boss Detective Superintendent Jayne Doherty said that despite his death, it gives his victims a peace of mind knowing he’s not out there anymore.</p> <p dir="ltr">“It was important for the victim survivors and that is why we persevered. We wanted to let them know we were not just guessing it was him. It also meant we are not still looking for someone that is still out there,” she said.</p> <p dir="ltr">“So those women who are walking down the street and are still wondering: Is that him? They now know that person is deceased.”</p> <p dir="ltr"><em>Images: The Daily Telegraph</em></p>

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Evidence that human evolution driven by major environmental pressures discovered

<p>The genes of ancient humans might have changed substantially due to environmental pressures and change, say an international team of researchers.</p> <p>A widely held belief related to human evolution is that our ancient ancestors’ ability to fashion tools, shelter, and use advanced communication skills may have helped to shield them from large environmental impacts such as changing climate, disease and exposure to other events affecting mortality.</p> <p>But research led out of Australian Centre for Ancient DNA at the University of Adelaide suggests that beneficial genes may have played a more important role in preserving our ancestors.</p> <p>Until now, the sudden increase in frequency of these genes in human groups was masked by the exchange of DNA between people during reproduction.</p> <p>Now, analyses of more than one thousand ancient genomes dating as far back as 45,000 years ago have found historic signals showing genetic adaptation was more common than previously thought.</p> <p>The study of evolutionary events, says the study’s co-lead author Dr Yassine Souilmi, has increased substantially in recent years, as these are the points where human genetics take historic turns.</p> <p>“Evolutionary events [are] exactly what shape our genetic diversity today,” Souilmi tells Cosmos.</p> <p>“That’s what makes us vulnerable to certain diseases [and] resistant to others.</p> <p>“Having a good understanding of evolution, we can have a better understanding of who we are.”</p> <p>Previous research by the Centre has uncovered a range of evolutionary trends, from historic climate change causing the demise of ancestral lions and bears, to the first interactions between humans and coronaviruses 20,000 years ago.</p> <p>And the broader field of research into ancient DNA has shed light on important moments in human history. Only recently did analyses of ancient genes uncover locations on the human genome associated with surviving Yersinia pestis – the bacterium that causes the bubonic plague.</p> <h2>Single events probably triggered selection</h2> <p>This study, published in Nature Ecology and Evolution, has similarly found environmental events might have been more influential on evolution among Eurasian groups.</p> <p>Such events might lead to a point of natural selection. Take, for instance, the emergence of a pathogen. If such a disease could kill people, those who managed to survive and continue reproducing would pass down favourable traits to subsequent generations.</p> <p>“Natural selection acts in two different mechanisms,” says Souilmi.</p> <p>“It only cares about whether you’re procreating successfully… when it acts, it’s either killing a lot of people, [preventing] some people from reproducing successfully, or some people are just not finding mates because they have some sort of ailment that’s not allowing them to mate successfully, or might make them undesirable.</p> <p>“What we’re finding is that the signal of natural selection we detected in this [research] was likely a single event, because the signal is clustered in time in a very early migration out of Africa.</p> <p>“Not all of the [events] we detected occurred at the same time, but the bulk of them did.”</p> <h2>A mirror to the present</h2> <p>This ‘agnostic’ study did not seek to identify the external pressures leading to the selection events indicated in these ancient genes, but future research by the team will seek to uncover that information.</p> <p>Studies like this, or those into specific pressures like the influence of the Black Death or coronaviruses on humans, show the impact of environmental change on our genetics.</p> <p>Souilmi says this is both insightful and cautionary, as environmental change in the present could be studied by humans in the future.</p> <p>He speculates that changes in the Earth’s climate, or the emergence of new pathogens, likely imposed selection pressures on ancient groups, whether through forcing shortages or changes to food supply or imposing physiological stressors.</p> <p>“Very likely, it’s the environment, the temperature, the weather patterns, that would have somewhat impacted the dietary regime of our ancestors out of Africa, and pathogens would have driven this [genetic] adaptation, which has shaped our genetic diversity now,” Souilmi says.</p> <p>“The direct lesson, socially, now, is that if we’re ever faced with events that are similar to that, we are not as immune to extreme episodes of adaptation where a lot of people might die, or be unable to reproduce.</p> <p>“Unless we do something to counteract the environmental changes, or viruses, bacterial or other pandemics, it could be a bad thing.”</p> <p><strong>This article originally appeared on <a href="https://cosmosmagazine.com/science/human-evolution-driven-by-environment/" target="_blank" rel="noopener">cosmosmagazine.com</a> and was written by Matthew Agius.</strong></p> <p><em>Image: Shutterstock</em></p>

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Neanderthals died out 40,000 years ago, but there has never been more of their DNA on Earth

<p>Neanderthals have served as a reflection of our own humanity since they were first discovered in <a href="https://www.nhm.ac.uk/discover/who-were-the-neanderthals.html" target="_blank" rel="noopener">1856</a>. What we think we know about them has been shaped and moulded to fit our cultural trends, social norms and scientific standards. They have changed from diseased specimens to primitive sub-human lumbering cousins to <a href="https://www.smithsonianmag.com/science-nature/rethinking-neanderthals-83341003/" target="_blank" rel="noopener">advanced humans</a>.</p> <p>We now know Homo neanderthalensis were very similar to ourselves and we even met them and frequently interbred. But why did they go extinct, while we <a href="https://global.oup.com/ukhe/product/the-cradle-of-humanity-9780198704539?cc=gb&amp;lang=en&amp;" target="_blank" rel="noopener">survived, flourished and ended up taking over the planet</a>?</p> <p>Neanderthals evolved over 400,000 years ago, most likely from an earlier ancestor <a href="https://humanorigins.si.edu/evidence/human-fossils/species/homo-heidelbergensis" target="_blank" rel="noopener">Homo heidelbergensis</a>. They were extremely successful and spread across an area from the Mediterranean to Siberia. They were highly intelligent, with brains on average <a href="https://www.livescience.com/60481-how-neanderthals-got-such-large-brains.html" target="_blank" rel="noopener">bigger than Homo sapiens‘s</a>.</p> <p>They hunted for <a href="https://theconversation.com/why-the-neanderthals-may-have-been-more-sophisticated-hunters-than-we-thought-new-study-98870" target="_blank" rel="noopener">big game</a>, collected plants, fungi, and seafood, controlled fire to cook, <a href="https://www.pnas.org/doi/10.1073/pnas.1907828116" target="_blank" rel="noopener">made composite tools</a>, made <a href="https://www.pnas.org/doi/10.1073/pnas.1112261109" target="_blank" rel="noopener">clothes from animal skins</a>, made beads from shells, and were able to <a href="https://www.pnas.org/doi/abs/10.1073/pnas.1411529111" target="_blank" rel="noopener">carve symbols on to cave walls</a>. They took care of their young, old and weak, created shelters for protection, lived through harsh winters and warm summers, and they buried their dead.</p> <p>Neanderthals did meet our ancestors on several occasions over the course of tens of thousands of years and the two species shared the European continent for at least 14,000 years. They even <a href="https://www.nature.com/articles/s41586-021-03335-3" target="_blank" rel="noopener">mated with each other</a>.</p> <h2>Death of a species</h2> <p>The most significant difference between Neanderthals and ourselves is that they went extinct about 40,000 years ago. The precise cause of their demise still eludes us, but we think it was probably the result of a combination of factors.</p> <p>First the climate of the last ice age was very variable, shifting from <a href="https://www.nature.com/articles/s41586-022-04600-9" target="_blank" rel="noopener">cold to warm and back again</a>, which put pressure on animal and plant food sources and meant Neanderthals constantly had to <a href="https://onlinelibrary.wiley.com/doi/abs/10.1111/jbi.12845" target="_blank" rel="noopener">adapt to environmental change</a>. Second there were never that many Neanderthals, with the overall population never exceeding the tens of thousands.</p> <p>They lived in groups of five to 15 individuals, compared with Homo Sapiens that had groups of up to <a href="https://theconversation.com/our-large-brains-evolved-thanks-to-an-ancient-arms-race-for-resources-and-mates-79183" target="_blank" rel="noopener">150 individuals</a>. These small isolated Neanderthal populations may have been increasingly genetically unsustainable.</p> <p>Third there was competition with other predators, particularly the <a href="https://theconversation.com/war-in-the-time-of-neanderthals-how-our-species-battled-for-supremacy-for-over-100-000-years-148205" target="_blank" rel="noopener">groups of modern humans</a> that emerged from Africa about 60,000 years ago. We speculate that many Neanderthals may have been assimilated into the larger bands of Homo sapiens.</p> <h2>Where’s the evidence?</h2> <p>Neanderthals left numerous traces for us to examine tens of thousands of years later, much of which can be seen at the special exhibition we have helped curate at the <a href="https://snm.ku.dk/english/exhibitions/neanderthal/" target="_blank" rel="noopener">Natural History Museum of Denmark</a>. Over the past 150 years we have collected fossil bones, stone and wooden tools, found trinkets and jewellery they left behind, uncovered burials, and now mapped their genome from ancient DNA. It seems that <a href="https://www.nature.com/articles/s41586-021-03335-3" target="_blank" rel="noopener">99.7% of Neanderthal</a> and modern human DNA is identical and they are our closest extinct relatives.</p> <p>Perhaps the most surprising fact was evidence of <a href="https://www.nature.com/articles/s41586-021-03335-3" target="_blank" rel="noopener">interbreeding</a> that has left traces of DNA in living humans today. Many Europeans and Asians have between 1% and 4% Neanderthal DNA while African people south of the Sahara have almost zero. Ironically, with a current world population of about 8 billion people, this means that there has never been more Neanderthal DNA on Earth.</p> <p>The Neanderthal genome also helps us understand more of what they looked like, as there is evidence that some Neanderthals evolved pale skin and red hair long before Homo sapiens. The many genes that are shared between Neanderthals and modern humans are linked to anything from the ability to taste bitter foods to the capacity to speak.</p> <p>We have also increased our knowledge of human health. For instance, some Neanderthal DNA that might have been beneficial to humans tens of thousands of years ago now seems to cause issues when combined with a modern western lifestyle.</p> <p>There are links to alcoholism, obesity, allergies, blood clotting, and <a href="https://institutions.newscientist.com/article/2077269-our-neanderthal-genes-linked-to-risk-of-depression-and-addiction" target="_blank" rel="noopener">depression</a>. Recently, scientists suggested an ancient gene variant from Neanderthals might increase the risk of <a href="https://www.pnas.org/doi/10.1073/pnas.2026309118" target="_blank" rel="noopener">serious complications from contracting COVID-19</a>.</p> <h2>Holding up a mirror</h2> <p>Like the dinosaurs, the Neanderthals didn’t know what was coming. The difference is that the dinosaurs disappeared suddenly following a giant meteorite hit from outer space. To the Neanderthals extinction happened gradually. They eventually lost their world, a comfortable home they had successfully occupied for hundreds of thousands of years that slowly turned against them, until existence itself was unsustainable.</p> <p>In that sense, Neanderthals now serve a different purpose. We see our reflection in them. They didn’t know what was happening to them and they had no choice but to continue down the road that eventually led to extinction. We on the other hand are painfully aware of our situation and the impact we have on this planet.</p> <p>Human activity is <a href="https://theconversation.com/climate-change-how-bad-could-the-future-be-if-we-do-nothing-159665" target="_blank" rel="noopener">changing the climate</a> and is leading straight into a sixth mass extinction. We can reflect on the mess we have landed ourselves in and we can do something about it.</p> <p>If we don’t want to end up like the Neanderthals, we better get our act together and collectively work for a more sustainable future. Neanderthal extinction reminds us that we should never take our existence for granted.</p> <p><strong>This article originally appeared on <a href="https://theconversation.com/neanderthals-died-out-40-000-years-ago-but-there-has-never-been-more-of-their-dna-on-earth-189021" target="_blank" rel="noopener">The Conversation</a>.</strong></p> <p><em>Image: Shutterstock</em></p>

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The Chase star’s royal connection

<p dir="ltr">Anne Hegerty, also known as The Governess on <em>The Chase</em> has been shocked to find out she is related to the Queen. </p> <p dir="ltr">Appearing on <em>DNA Journey</em>, the quiz master was surprised to find out what her grandmother had always told her was in fact true - the Queen is her 19th cousin.</p> <p dir="ltr">The 63-year-old said she never believed her grandmother when she told her because she “was the most tremendous liar”. </p> <p dir="ltr">The relation comes from her mother’s side where they are related to the Hayes family one of whom married Robert the Bruce’s daughter Princess Elizabeth in 1370.</p> <p dir="ltr">This then resulted with the Queen being Anne’s 19th cousin. </p> <p dir="ltr">Anne confessed that while growing up, her mother disapproved of knowing the ancestry line. </p> <p dir="ltr">“She’d say, ‘it doesn’t prove a thing, dear’,” Anne told <a href="https://www.thesun.co.uk/tv/18165272/queen-cousin-anne-hegarty/" target="_blank" rel="noopener">The Sun</a>. </p> <p dir="ltr">“As a child I was always curious about this stuff and my mother was always very repressive.</p> <p dir="ltr">“I think it was because on my mother’s mother’s side there’s quite a bit of posh, and my mum thought I’d grow up to be a terrible snob.</p> <p dir="ltr">“But I’ve already grown up to be a terrible snob, so really there’s nothing to hide.”</p> <p dir="ltr"><em>Image: Instagram </em></p>

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Women discover after 55 years that they were switched at birth

<p>Two women are suing the hospital where they were both born in 1964, after they discovered they were switched at birth.</p> <p>Jill Lopez and Tina Ennis, both 57, discovered the mix-up at the hands of the Oklahoma hospital after learning the truth from an at-home DNA test through Ancestry.com.</p> <p>The women were both born at Duncan Physicians and Surgeons Hospital on May 18th 1964, but somehow claim they were each handed off to the other's biological parents.</p> <p>Jill and Tina went 55 years without knowing the truth, until Tina sent her DNA off to Ancestry.com and received confusing results.</p> <p>With the help of her daughter and extensive internet research, Tina tracked down Jill, who took her own DNA test and confirmed that she is the actual biological daughter of Ennis' mother, Kathryn Jones.</p> <p>The two women are now suing the hospital they were switched in for recklessness and negligent infliction of emotional distress.</p> <p>Both families had no idea about the devastating mix-up until recently, and are now left struggling with the revelation.</p> <p>Kathryn Jones said one of the worst parts of the discovery was realising her grandchildren were not biologically hers either.</p> <p>"It was like somebody had ripped out a part of my heart,' Jones said. 'I just couldn't deal with it."</p> <p>Since the news broke, Jill has been spending time with her biological mother, leaving Tina heartbroken when she realised her biological parents, Joyce and John, had both passed away.</p> <p>"Jill got to be with my real parents, and now she gets to be with my parents I grew up with," Tina said.</p> <p>"I didn’t know what to think about it at first, but the more I think about it, it makes me really sad."</p> <p>Together with Kathryn Jones, Tina and Jill have filed their suit against the hospital, who are fighting back.</p> <p><em>Image credits: Facebook</em></p>

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Is the secret to a long life written in our DNA?

<p><em>Image: Getty </em></p> <div> <h2>Genes that protect us from disease in our early years could be quietened to ward off ageing.</h2> <div class="copy"> <p>The quest for immortality may seem the stuff of science fiction, but evidence is emerging that our lifespans could be extended well beyond current averages. Although some studies point to an inescapable limit of around 150 years old for humans, this still leaves us with a clear gap between our current life expectancy and our potential maximum.</p> <p>A new study, published in <em>Genome Research</em>, has identified a group of genes that could play an essential role in bridging this divide.</p> <p>The study, led by University College London (UCL) researchers in the UK, looked at genes that have previously been linked to long lifespans in small organisms like fruit flies, finding a link in humans as well.</p> <p>The genes in question play an essential role in building proteins in our cells. Co-lead author Dr Nazif Alic from the Institute of Healthy Ageing at UCL says that quietening the actions of genes such as these can affect longevity.</p> <p>“We have already seen from extensive previous research that inhibiting certain genes – involved in making proteins in our cells – can extend lifespan in model organisms such as yeast, worms and flies,” he says.</p> <p>This is the first time scientists have demonstrated the same link in humans.</p> <p>The results emerged from a review of genetic data from previous studies involving 11,262 people who had lived an exceptionally long life, to an age above the 90<sup>th</sup> percentile of their cohort. They found that people with reduced activity of genes linked to two RNA polymerase enzymes were more likely to live very long lives.</p> <p>They found evidence that the genes’ effects were linked to their expression in specific organs, including abdominal fat, liver, and skeletal muscle, but also that the effect on longevity was much broader, transcending direct associations with specific age-related diseases.</p> <p>Does this mean we can simply switch these genes off if we want to have a crack at a second century of life?</p> <p>Not quite.</p> <p>There’s a trade-off involved with the activity of these genes, with loss of function earlier in life associated with disorders known as ribosomopathies. This is an example of a concept known as antagonistic pleiotropy, where genes that shorten our lives are selected for in evolution if they help us early in life and through our child-bearing years.</p> <p>“Here, we have found that inhibiting these genes may also increase longevity in people, perhaps because they are most useful early in life before causing problems in late life,” says Alic.</p> <p>Clearly we need to hold on to these genes in our youth, but the findings suggest that existing drugs such as rapamycin, an immune regulator which acts to inhibit certain polymerase enzymes, could be used to promote healthy lifespan once we’ve cleared the hurdle of middle-age.</p> <p>Professor Karoline Kuchenbaecker from the UCL Genetics Institute is enthusiastic about the results of this study, saying that bridging the gap between animal models and human applications, as this study did, is essential in the study of healthy ageing.</p> <p>“Ageing research in model organisms, such as flies, and in humans are often separate efforts,” she says. “Here we are trying to change this.</p> <p>“In flies, we can experimentally manipulate ageing genes and investigate mechanisms. But ultimately, we want to understand how ageing works in humans. Bringing the two fields together has the potential to overcome the limitations of both fields.”</p> <!-- Start of tracking content syndication. Please do not remove this section as it allows us to keep track of republished articles --> <img id="cosmos-post-tracker" style="opacity: 0; height: 1px!important; width: 1px!important; border: 0!important; position: absolute!important; z-index: -1!important;" src="https://syndication.cosmosmagazine.com/?id=180257&amp;title=Is+the+secret+to+a+long+life+written+in+our+DNA%3F" alt="" width="1" height="1" /> <!-- End of tracking content syndication --></div> <div id="contributors"> <p><a href="https://cosmosmagazine.com/science/biology/secret-to-long-life-in-dna/">This article</a> was originally published on <a href="https://cosmosmagazine.com">Cosmos Magazine</a> and was written by <a href="https://cosmosmagazine.com/contributor/jamie-priest">Jamie Priest</a>.</p> </div> </div>

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Patient zero of Black Death found

<p><span style="font-weight: 400;">New evidence has suggested a man who died 5300 years ago in Latvia was infected with the earliest-known strain of the plague that caused the Black Death.</span></p> <p><span style="font-weight: 400;">Waves of the plague swept through Europe for several centuries from the 1300s, causing millions of deaths.</span></p> <p><span style="font-weight: 400;">“Up to now this is the oldest-identified plague victim we have,” Dr Ben Krause-Kyora of the University of Kiel in Germany said of the remains.</span></p> <p><span style="font-weight: 400;">The man was buried with three others at a Neolithic burial site in Latvia near the River Salac, which connects to the Baltic Sea.</span></p> <p><span style="font-weight: 400;">The research, published in </span><em><span style="font-weight: 400;">Cell Reports</span></em><span style="font-weight: 400;">, involved the sequencing of the DNA from the bones and teeth of the four individuals.</span></p> <p><img style="width: 500px; height:375px;" src="https://oversixtydev.blob.core.windows.net/media/7842261/60da287e1477f300188c82ae.jpg" alt="Dominik Göldner / BGAEU" data-udi="umb://media/1f7ae3fb0a0c41a49c6b87ea085cbef8" /></p> <p><span style="font-weight: 400;">When the bodies were tested for bacteria and viruses, the researchers were surprised to find one hunter-gatherer - a man in his twenties - was infected with an ancient strain of the plague, caused by the </span><span style="font-weight: 400;">Yersinia pestis</span><span style="font-weight: 400;"> bacterium.</span></p> <p><span style="font-weight: 400;">“He was most likely bitten by a rodent, got the primary infection of </span><span style="font-weight: 400;">Yersinia pestis</span><span style="font-weight: 400;"> and died a couple of days [later] - maybe a week later - from the septic shock,” said Dr Krause-Kyora.</span></p> <p><span style="font-weight: 400;">The researchers suggest that this strain appeared about 7000 years ago at the same time that agriculture started to appear in central Europe.</span></p> <p><span style="font-weight: 400;">They also believe the bacterium may have sporadically jumped from animals to humans and that it became better at infecting humans over time, evolving into the form known as the bubonic plague.</span></p> <p><span style="font-weight: 400;">The research has been welcomed by other experts, though it doesn’t rule out the hypothesis that the disease was spreading throughout Europe at the time.</span></p> <p><span style="font-weight: 400;">Though the disease is still around today, it is treatable with antibiotics if caught early.</span></p> <p><em><span style="font-weight: 400;">Images: </span><span style="font-weight: 400;">Dominik Göldner / BGAEU</span></em></p>

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A man makes a shocking discovery after DNA test

<p><span style="font-weight: 400;">A man who took a DNA test found an uncomfortable truth in his genes that makes a long-running family joke much more awkward.</span></p> <p><span style="font-weight: 400;">The man posted his story anonymously on Reddit, sharing his desire to bust the family joke his father would make that the family was related to Sir Arthur Conan Doyle, who penned </span><span style="font-weight: 400;">Sherlock Holmes</span><span style="font-weight: 400;">.</span></p> <p><span style="font-weight: 400;">The 27-year-old, whose parents divorced when he was only one year old, was discouraged from taking a DNA test to look into his family history by his mother.</span></p> <p><span style="font-weight: 400;">Assuming she merely did not want him wasting money on a potentially inaccurate test, he took one anyway.</span></p> <p><span style="font-weight: 400;">“This isn’t too far from expected for her, she’s a very financially conscious person and said that I shouldn’t waste my money on something silly like a DNA test,” he wrote in the post.</span></p> <p><span style="font-weight: 400;">When he got the results, he said they “shook [him] to my core”.</span></p> <p><span style="font-weight: 400;">The man discovered his biological father was not who raised him, but his ‘dad’s’ best friend.</span></p> <p><span style="font-weight: 400;">On his mother’s side, the family tree was as he expected, writing, “I saw cousins, aunts, and uncles who all had used the same DNA service that I had.”</span></p> <p><span style="font-weight: 400;">When he looked at his father’s side, he saw a list of names he recognised but were “just not my family as I had known it”.</span></p> <p><span style="font-weight: 400;">Bringing up the discovery with his father, the man said he “took it in his stride” and “immediately averted his worst fear” by assuring him it would not affect their relationship.</span></p> <p><span style="font-weight: 400;">“This man has paid child support, invested his efforts and time, and worked multiple jobs at a time to afford me the best life he could aadn biologically I’m not even his,” he said.</span></p> <p><span style="font-weight: 400;">The discovery of his mother’s affair instead proved to be the “real twist”.</span></p> <p><span style="font-weight: 400;">“I grew up with this other guy’s daughters (my apparent half-sisters) and wife as close family friends,” he continued.</span></p> <p><span style="font-weight: 400;">Now facing “a quandary” of whether to reach out to his “apparent biological father”, the man explained his biological dad has been married for 26 years.</span></p> <p><span style="font-weight: 400;">He even noted that the pair shared similar physical characteristics.</span></p> <p><span style="font-weight: 400;">“Fun family anecdote has always been that he ‘rubbed off on me’ because we share a cleft chin,” the Redditor explained.</span></p> <p><span style="font-weight: 400;">“Makes sense now.”</span></p>

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Is racism and bigotry in our DNA?

<p><em>Is bigotry in our DNA, a remnant of our fear of “the other” way back when that was necessary? If so, why do some battle with their instincts while others embrace them?</em> Peter, 71, Darlington</p> <blockquote> <p>I, Pencil, simple though I appear to be, merit your wonder and awe … if you can become aware of the miraculousness which I symbolise, you can help save the freedom mankind is so unhappily losing. I have a profound lesson to teach. And I can teach this lesson better than can an automobile or an airplane or a mechanical dishwasher because — well, because I am seemingly so simple.</p> <p>Simple? Yet, not a single person on the face of this Earth knows how to make me.</p> </blockquote> <p>Humans are the <a href="https://theconversation.com/sino-tibetan-populations-shed-light-on-human-cooperation-49469">most cooperative species</a> on the planet – all part of a huge interconnected ecosystem. We have built vast cities, connected by a global nervous system of roads, shipping lanes and optical fibres. We have sent thousands of satellites spinning around the planet. Even seemingly simple objects like a graphite pencil are the work of thousands of hands from around the world, as the wonderful essay <a href="http://www.econlib.org/library/Essays/rdPncl1.html#firstpage-bar">I-Pencil</a>, quoted above, by <a href="https://www.nytimes.com/1983/05/16/obituaries/leonard-e-read-dies-free-market-advocate.html">Leonard Read</a> describes.</p> <p>Yet we can also be surprisingly intolerant of each other. If we are completely honest, there is perhaps a little bit of xenophobia, racism, sexism and bigotry <a href="https://theconversation.com/think-youre-all-for-gender-equality-your-unconscious-may-have-other-ideas-69520">deep within all of us</a>, if we would only allow it. Luckily, we can choose to control and suppress such tendencies for our own wellbeing and the good of society.</p> <p>Most human attitudes and behaviour <a href="https://theconversation.com/nature-versus-nurture-how-modern-science-is-rewriting-it-127472">have both a genetic and an environmental component</a>. This is also true for our fear of others who are different to us — xenophobia — and intolerance of their viewpoints — bigotry. Hardwired into the brain’s amygdala region <a href="https://www.smithsonianmag.com/science-nature/what-happens-brain-feel-fear-180966992/">is a fear reflex</a> that is primed by encounters with the unfamiliar.</p> <p>In premodern times, it made sense to be fearful of other groups. They might be violent, steal our resources, or introduce new diseases we are not adapted to. Conversely, it was beneficial to trust those who look similar to us — they are more likely to be related. And when <a href="https://science.sciencemag.org/content/327/5971/1341">we help these kin</a>, our own genes are more likely to be passed to future generations. What’s more, if the other person reciprocates the good deed, we benefit even more.</p> <p>Beyond such genetic influences, our human culture strongly influences our attitudes and behaviour, modifying innate human drives – either suppressing them or encouraging them further. Whether we tolerate and trust someone or fear and reject them depends a lot on this culture.</p> <p>Modern civilisation in general encourages the extension of attitudes such as respect and tolerance beyond those who look similar to us, to those who we have no relation to. We reinforce and codify these values, teaching them to our children, while religious and secular spiritual leaders promote them in their teachings. That’s because they generally lead to a more harmonious, mutually-beneficial society.</p> <p><strong>The trouble with tribalism</strong></p> <p>This is exactly what has made us such a cooperative species. But sometimes our cultures can be less progressive. What people around us say and do subconsciously influences the way we think. We soak up this cultural context like a sponge, and it subtly shapes our attitudes and behaviours. If we are surrounded by people that stigmatise those different to themselves, this also encourages distrust or aggression in us.</p> <p>It presses the buttons of certain deep-seated xenophobic attitudes within us. In fact, it discourages hard-learned inhibitory responses in the brain’s <a href="https://www.sciencedirect.com/science/article/pii/S0962184907000327?via%3Dihub">prefrontal cortex</a> that get built up under more progressive contexts.</p> <p>Movements such as Nazism have openly promoted xenophobia and bigotry. They encourage a strong tribal loyalty to the “in-group” (one’s own group), while stigmatising (and in the case of Nazism, executing) others. Taken too far, a healthy pride in one’s country can easily tip into unhealthy nationalism, where we identify with our own nation at the exclusion of others.</p> <p>Things seem to be moving in this direction today. Leaders such as US president, Donald Trump, Brazilian president, Jair Bolsonaro and Indian prime minister, Narendra Modi, are more frequently taking centre stage. In the UK, figures such as Nigel Farage, a key architect of Brexit, uses media platforms to promote naive and bigoted views – an example being <a href="https://twitter.com/Nigel_Farage/status/1240341861119791104?s=20">this tweet</a> about the 2020 coronavirus outbreak: “It really is about time we all said it. China caused this nightmare. Period.”</p> <p>When the media, and especially people we trust, talk in such a way, it has a profound effect on our receiving minds. It can even shape our beliefs in what we might think are purely rational issues. For example, the belief in whether humans are causing climate change <a href="https://journals.sagepub.com/doi/pdf/10.1177/1745691617748966">is strongly associated</a> with US political party membership.</p> <p>This is because we tend to adopt a common position on a topic to signal we are part of a group, just like football fans wear certain colours or have tattoos to show their tribal loyalty. Even strong individuals who stand up to oppressive regimes typically <a href="https://theconversation.com/would-you-stand-up-to-an-oppressive-regime-or-would-you-conform-heres-the-science-124469">have shared ideals and norms</a> with other members of a resistance movement.</p> <p>This tribalism can all feel very visceral and natural because, well, in a way, it is. It fires up the primal parts of our brain designed for such responses. Yet, there are other natural attitudes, such as compassion and consideration for others, that can be suppressed in such circumstances. Imbalanced cultures produce imbalanced brains.</p> <p>This combination of nature and nurture shaping our attitudes and behaviour is apparent in many human characteristics, and unpicking some of these examples can help us see opportunities to steer the process.</p> <p>Consider the tendency to become overweight in modern society. In premodern times, sugary and fatty foods <a href="https://www.businessinsider.com/evolutionary-reason-we-love-sugar-2014-4?r=US&amp;IR=T">were rare and valuable</a> for humans. Now, they are everywhere. A biological trait – the craving for sugary or fatty foods – which was adaptive in premodern times, has become detrimental and maladaptive.</p> <p>Surely our modern cultures can protect us from these innate drives when they are unhealthy for ourselves and society? After all, we effectively suppress violent behaviour in society through the way we bring up children, policing and the prison system.</p> <p>Instead of acknowledging and protecting us from the innate drive to binge on unhealthy food, however, our modern cultures (in many countries at least) actually exacerbate that particular problem. The result is <a href="http://www.healthdata.org/news-release/nearly-one-third-world%E2%80%99s-population-obese-or-overweight-new-data-show">2 billion people</a> – over a quarter of the world’s population – overweight or obese, while another 2 billion <a href="https://globalnutritionreport.org/reports/global-nutrition-report-2018/">suffer some kind of micronutrient deficiency</a>.</p> <p>When we understand how our hardwired urges interact with an unhelpful cultural context, we can begin to design positive interventions. In the case of obesity, this might mean less junk food marketing and altering the composition of manufactured food. We can also change our own behaviour, for example laying down new routines and healthier eating habits.</p> <p><strong>Climate change could boost bigotry</strong></p> <p>But what about bigotry and xenophobia? Can’t we simply design the right fixes for them? That may depend on how big the problems we face in future are. For example, growing ecological crises – climate change, pollution and biodiversity loss – may actually lead to more bigoted and xenophobic attitudes.</p> <p>Cultural psychologist <a href="https://www.michelegelfand.com/about">Michele Gelfand</a> has shown how environmental shocks <a href="https://science.sciencemag.org/content/332/6033/1100">cause societies to become “tighter”</a> – meaning the tendency to be loyal to the “in-group” gets stronger. Such societies are more likely to elect authoritarian leaders and to <a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221953">show prejudice</a> towards outsiders.</p> <p>This has been observed under past ecological threats such as resource scarcity and disease outbreaks, and under climate change scenarios we expect these threats, in particular extreme weather events and food insecurity, to only get worse. The same goes for the coronavirus pandemic. While many hope such outbreaks <a href="https://theconversation.com/philosopher-in-italian-coronavirus-lockdown-on-how-to-think-positively-about-isolation-133859">can lead to a better world</a>, they could do exactly the opposite.</p> <p>This enhanced loyalty to our local tribe is a defence mechanism that helped past human groups pull together and overcome hardship. But it is <a href="https://theconversation.com/climate-change-how-do-i-cope-with-our-planets-inevitable-decline-128593">not beneficial in a globalised world</a>, where ecological issues and our economies transcend national boundaries. In response to global issues, becoming bigoted, xenophobic and reducing cooperation with other countries will only make the impacts on own nations worse.</p> <p>Back in 2001, a United Nations initiative called the <a href="http://www.millenniumassessment.org/en/Products.Synthesis.aspx">Millennium Ecosystem Assessment</a> sought to take stock of global environmental trends and, crucially, to explore how these trends might unfold in future. One of the scenarios was called “Order from Strength” and represented “a regionalised and fragmented world that is concerned with security and protection … Nations see looking after their own interests as the best defence against economic insecurity, and the movement of goods, people, and information is strongly regulated and policed”.</p> <p>Later iterations of the scenario <a href="https://greattransition.org/fortress-world">have been dubbed “Fortress world”</a> describing a dystopian vision where order is imposed through an authoritarian system of global apartheid with elites in protected enclaves and an impoverished majority outside.</p> <p>When you think about how Trump talks about building a wall on the Mexico border, encouraged by chants from the crowd, we have to wonder how close we are to this scenario. On a larger scale, the rich “developed” countries primarily responsible for causing climate change are doing very little to address the plight of poorer countries.</p> <p>There seems to be a lack of empathy, a disregard and intolerance for others who were not lucky enough to be born in “our” tribe. In response to an ecological catastrophe of their making, rich countries simply argue about how best to prevent the potential influx of migrants.</p> <p><strong>Rewiring the brain</strong></p> <p>Thankfully, we can use rational thinking to develop strategies to overcome these attitudes. We can reinforce positive values, building trust and compassion, reducing the distinction between our in-group and the “other”.</p> <p>An important first step is appreciating our connectedness to other people. We all evolved from the same bacteria-like ancestor, and right now we share over 99% of our DNA with everyone else on the planet. Our minds are closely linked through social networks, and the things we create are often the inevitable next step in a series of interdependent innovations.</p> <p>Innovation is part of a great, linked creative human endeavour with no respect for race or national boundaries. In the face of overwhelming evidence from multiple scientific disciplines (biology, psychology, neuroscience) you can even question whether we exist as discrete individuals, or whether this sense individuality is an illusion (as I argue in my book <a href="https://www.amazon.co.uk/Self-Delusion-Connected-Everyone-Matters/dp/1474611745/">The Self Delusion</a>).</p> <p>We <a href="https://www.sciencefocus.com/the-human-body/the-illusion-of-individualism-helped-us-succeed-as-a-species-but-now-the-scales-are-tipping/">evolved to believe</a> we are discrete individuals because it brought survival benefits (such as memory formation and an ability to <a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/(SICI)1520-6505(1998)6:5%3C178::AID-EVAN5%3E3.0.CO;2-8">track complex social interactions</a>). But taken too far, self-centred individualism can prevent us from solving collective problems.</p> <p>Beyond theory, practice is also necessary to literally rewire our brains – reinforcing the neural networks through which compassionate behaviour arises. Outdoor community activities <a href="https://link.springer.com/article/10.1007/s11625-018-0542-9">have been shown to</a> increase our psychological connectedness to others. Similarly, meditation approaches alter neural networks in the brain and reduce our sense of <a href="https://www.pnas.org/content/108/50/20254">isolated self-identity</a>, instead promoting compassion towards others. Even computer games and books can be <a href="https://www.nature.com/articles/s41539-018-0029-6">designed to increase empathy</a>.</p> <p>Finally, at the societal level, we need frank and open debate about environmental change and its current and future human impacts – crucially, how our attitudes and values can affect other lives and livelihoods. We need public dialogue around climate-driven human migration and how we respond to that as a society, allowing us to mitigate the knee-jerk reaction of devaluing others.</p> <p>Let’s defuse this ticking ethical timebomb and shame those who stoke flames of bigotry beneath it. Instead, we can open ourselves up to a more expansive attitude of connectedness, empowering us to work together in cooperation with our fellow human kin.</p> <p>It is possible to steer our cultures and rewire our brains so that xenophobia and bigotry all but disappear. Indeed, working collaboratively across borders to overcome the global challenges of the 21st century relies upon us doing just that.</p> <p><span><a href="https://theconversation.com/profiles/tom-oliver-585521"><em>Tom Oliver</em></a><em>, Professor of Applied Ecology, <a href="https://theconversation.com/institutions/university-of-reading-902">University of Reading</a></em></span></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/is-racism-and-bigotry-in-our-dna-135096">original article</a>.</em></p>

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New study shows that animal's lifespan is written in its DNA

<p>Humans have a “natural” lifespan of around 38 years, according to a new method we have developed for estimating the lifespans of different species by analysing their DNA.</p> <p>Extrapolating from genetic studies of species with known lifespans, we found that the extinct woolly mammoth probably lived around 60 years and bowhead whales can expect to enjoy more than two and a half centuries of life.</p> <p>Our research, <a href="https://www.nature.com/articles/s41598-019-54447-w">published today in Scientific Reports</a>, looked at how DNA changes as an animal ages – and found that it varies from species to species and is related to how long the animal is likely to live.</p> <p><strong>The mystery of ageing</strong></p> <p>The ageing process is very important in biomedical and ecological research. As animals grow older, they experience a decline of biological functions, which limits their lifespan. Until now it has been difficult to determine how many years an animal can live.</p> <p>DNA is the blueprint of living organisms and it is an obvious place to seek insights into ageing and lifespan. However, no-one has been able to find differences in DNA sequences that account for differences in lifespans.</p> <p>Lifespans among vertebrates varies greatly. The pygmy goby (<em>Eviota sigillata</em>) is a small fish that lives only eight weeks, whereas individual Greenland sharks (<em>Somniosus microcephalus</em>) have been found that lived for more than 400 years.</p> <p>Knowing the lifespan of wild animals is fundamental for wildlife management and conservation. For endangered species, lifespan can be used to understand what populations are viable. In industries such as fisheries, lifespan is used in population models to determine catch limits.</p> <p>However, the lifespan of most animals is unknown. Most estimates come from a small number of individuals living in captivity whose ages at death were known. For long-lived species it is difficult to obtain a lifespan as they may outlive a generation of researchers.</p> <p><strong>Using changes in DNA to measure age</strong></p> <p>Over the past few years researchers have developed DNA “clocks” that can determine how old an animal is using a special type of change in the DNA called DNA methylation.</p> <p>DNA methylation does not change the underlying sequence of a gene but controls whether it is active. Other researchers have shown that DNA methylation in specific genes is associated with the maximum lifespan of some mammals such as primates.</p> <p>Despite DNA methylation being linked to ageing and lifespan, no research until now has used it as a method to estimate the lifespan of animals.</p> <p>In our research, we have used 252 genomes (full DNA sequences) of vertebrate species that other researchers have assembled and made publicly available in an <a href="https://www.ncbi.nlm.nih.gov/genome/">online database</a>. We then compared these genomes to <a href="https://genomics.senescence.info/species/">another database</a> of known animal lifespans.</p> <p>Using this data, we found that we could estimate the lifespan of vertebrate species by looking at where DNA methylation occurs in 42 particular genes. This method also lets us estimate the lifespans of long-lived and extinct species.</p> <p style="text-align: center;"><em><a href="https://images.theconversation.com/files/306222/original/file-20191211-95138-nfsxg8.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=1000&amp;fit=clip"><img src="https://images.theconversation.com/files/306222/original/file-20191211-95138-nfsxg8.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip" alt="" /></a> <span class="caption">Using DNA analysis, scientists can now estimate the lifespans of long-lived and extinct species.</span> <span class="attribution"><span class="source">CSIRO</span>, <span class="license">Author provided</span></span></em></p> <p style="text-align: left;"><strong>Extinct species</strong></p> <p>We found the lifespan of the bowhead whale, thought to be the world’s longest lived mammal, is 268 years. This estimate is 57 years higher than the oldest individual that has been found, so they may have a much longer lifespan than previously thought.</p> <p>We also found the extinct woolly mammoth had a lifespan of 60 years, similar to the 65-year span of the modern-day African elephant.</p> <p>The extinct Pinta Island giant tortoise had a lifespan of 120 years by our estimate. The last member of this species, Lonesome George, died in 2012 at age 112.</p> <p>Interestingly, we found Neanderthals and Denisovans, which are extinct species closely related to modern humans, had a maximum lifespan of 37.8 years.</p> <p>Based on DNA, we also estimated a “natural” lifespan modern humans of 38 years. This matches some anthropological estimates for early modern humans. However, humans today may be an exception to this study as advances in medicine and lifestyle have extended the average lifespan.</p> <p>As more scientists assemble the genomes of other animals, our method means their lifespans can readily be estimated. This has huge ecological and conservation significance for many species which require better wildlife management.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important; text-shadow: none !important;" src="https://counter.theconversation.com/content/128623/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: http://theconversation.com/republishing-guidelines --></p> <p><em><a href="https://theconversation.com/profiles/benjamin-mayne-908831">Benjamin Mayne</a>, Molecular biologist and bioinformatician, <a href="http://theconversation.com/institutions/csiro-1035">CSIRO</a></em></p> <p><em>This article is republished from <a href="http://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/a-new-study-shows-an-animals-lifespan-is-written-in-the-dna-for-humans-its-38-years-128623">original article</a>.</em></p>

Family & Pets

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Loch Ness monster: DNA analysis brings new theory to light

<p><span>The mystery creatures behind the thousand sightings of the fabled Loch Ness Monster may be giant eels, a group of scientists said.</span></p> <p><span>The legend of the giant sea monster has persisted throughout the decades, with some theorising that the creature could be a Jurassic-era reptile, a huge fish, circus elephants, or dinosaurs suspected of surviving extinction such as plesiosaur or elasmosaurus.</span></p> <p><span>Following an analysis of 250 water samples from Loch Ness in Scotland, a team of environmental DNA experts found no evidence for prehistoric reptiles, otters, seals, sharks, catifsh or huge fish such as sturgeons.</span></p> <p><span>However, they discovered a lot of genetic material from eels. </span></p> <p><span>“Is there a plesiosaur in Loch Ness? No. There is absolutely no evidence of any reptilian sequences,” said Professor Neil Gemmell, a geneticist from University of Otago and the study’s leader.</span></p> <p><span>“So I think we can be fairly sure that there is probably not a giant scaly reptile swimming around in Loch Ness.”</span></p> <p><span>Gemmell said the “very significant amount” of eel DNA suggests that the ray-finned fish might be the creature people have been seeing.</span></p> <p><span>“The sheer quantity of the material says that we can’t discount the possibility that there may be giant eels in Loch Ness. Therefore we can’t discount the possibility that what people see and believe is the Loch Ness Monster might be a giant eel.”</span></p> <p><span>The Loch Ness Monster has continued to remain as Scotland’s most enduring myths.</span></p> <p><span>The most famous picture of Nessie, taken by British surgeon Robert Wilson in 1934, was later revealed to be a hoax that used a wood putty model on a toy submarine. However, that does not stop people from attempting to track down the beast in the years since.</span></p> <p><span>Steve Feltham, the world record holder for the longest continuous Loch Ness Monster vigil, said he is not convinced the researchers have identified the monster.</span></p> <p><span>“A 12-year-old boy could tell you there are eels in Loch Ness,” he told <em><a href="https://www.bbc.com/news/uk-scotland-highlands-islands-49495145">BBC</a>.</em> “I caught eels in the loch when I was a 12-year-old boy.”</span></p>

News

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Should I get my DNA tested?

<p>With the advent of online ancestry DNA testing, and advancements in genetic screening for various medical aliments, we’re able to know more than ever about the genes that make us who we are.</p> <p>But is there a point to knowing we’re 25 per cent Irish? And is there a point to knowing we could one day be struck down with a disease we’re unable to prevent?</p> <p>We asked five experts if we should consider a DNA test.</p> <p><strong>Four out of five experts said yes</strong></p> <p><img src="https://images.theconversation.com/files/259889/original/file-20190220-148520-121cdzg.png?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip" alt="" /> <span class="caption"></span></p> <p>Here are their detailed responses:</p> <p><iframe id="tc-infographic-427" class="tc-infographic" height="400px" src="https://cdn.theconversation.com/infographics/427/45901c723a843d0a712aa7bdf2ed8f27399293a3/site/index.html" width="100%" style="border: none;" frameborder="0"></iframe></p> <p> </p> <p><img src="https://images.theconversation.com/files/210303/original/file-20180314-113452-h7un11.png?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip" alt="" /> <span class="caption"></span></p> <p><em>None of the authors have any interests or affiliations to declare.</em><!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important; text-shadow: none !important;" src="https://counter.theconversation.com/content/120664/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: http://theconversation.com/republishing-guidelines --></p> <p><span><em>Written by Alexandra Hansen, Chief of Staff, The Conversation. Republished with permission of </em><a rel="noopener" href="https://theconversation.com/should-i-get-my-dna-tested-we-asked-five-experts-120664" target="_blank"><em>The Conversation</em></a><em>. </em></span></p>

Mind

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Fast moves to slow down ageing

<p>We've known for decades that exercise is a great anti-ager when it comes to how we look and how we function. It keeps pot bellies at bay by burning kilojoules and fights frailty by building stronger muscles – but that's just the tip of the iceberg. It may also have the power to work deep down in our cells to slow biological ageing. </p> <p>At Australia's Victoria's Federation University, molecular biologist Fadi Charchar is looking at how exercise affects the tiny caps called telomeres on the end of strands of DNA.  Often compared to the tags that protect the tips of shoelaces, telomeres do a similar job with our DNA – they help protect it from damage. At least they do when they're in good shape. When they start to fray and shrink as they can with the influence of age and bad habits like smoking, our DNA is more likely to deteriorate and increase our risk of disease.  </p> <p>But in the last few years a number of studies have found that when people do regular exercise, especially moderate to intense aerobic exercise, their telomeres don't degrade as quickly, explains Professor Charchar of the University's Faculty of Science and Technology.</p> <p>"Now some studies are showing that exercise can actually lengthen telomeres," he says.  </p> <p>Two years ago his own study of a small group of 40-ish ultra marathon runners  who typically ran 40 to 100 kilometres a week found that, compared to sedentary people, their telomeres were 11 per cent longer – something which knocked 16 years off their biological age.  He's since repeated the study comparing athletes to sedentary people and again found that the athletes' telomeres were longer.</p> <p>Still, says Chachar, you may not need to run  marathons to do your telomeres  a good turn – as the New York Times reported recently,  US research looking at the exercise habits of 6500 people taking part in the National Health and Nutrition Examination Survey, linked even modest amounts of physical activity with a three per cent lower risk of having very short telomeres, but the odds improved dramatically in people who moved the most and who varied the kind of exercise they did – their risk of very short telomeres was almost 60 per cent lower.</p> <p>So what is it about exercise that could have this positive effect? We often assume that exercise improves our health by delivering more oxygen to our body, but in his research Fadi Charchar found that the effect on telomeres was independent of oxygen uptake.</p> <p>"We don't know the exact mechanism but we think it might be the effect of a gene called TERT which helps maintain and lengthen telomeres – our research has found that exercise may enhance the function of TERT," he says. "In addition exercise causes changes in the DNA structure itself that can result in considerable benefits to cells that can be passed on to future generations in sperm cells."</p> <p>But this link between exercise and longer telomeres is just part of the much bigger picture of epigenetics, the field of science that looks at how our lifestyle habits and environment can change how our genes behave in our body for good or bad, says Charchar.</p> <p>"There's been an explosion of research into how our lifestyle can influence our health at a cellular level," he says.</p> <p>Still, there are a lot of unanswered questions about exercise and telomeres – like what kind of exercise is optimal and how much should we do for the best effect?  So far, aerobic exercise is looking good, says Chachar.</p> <p>"We've just done a study into the effects of resistance training on telomeres and we found that it helps a bit but not as much as aerobic exercise does," he adds.  </p> <p>It's no surprise that already there are anti-ageing supplements claiming to protect telomeres starting to make an appearance online, often with high price tags. But for now, the best – and cheapest bet – looks like a run or a walk in the park.  </p> <p>First appeared on <a href="http://www.Stuff.co.nz" target="_blank"><span style="text-decoration: underline;"><strong>Stuff.co.nz</strong></span></a>.</p> <p><strong>Related links:</strong></p> <p><span style="text-decoration: underline;"><em><strong><a href="/health/caring/2015/12/centenarian-credits-hot-dogs-for-long-life/">100-year-old woman reveals her unexpected secret to longevity: hot dogs</a></strong></em></span></p> <p><span style="text-decoration: underline;"><em><strong><a href="/health/caring/2015/12/elderly-couple-recreate-their-wedding-day/">98-year-old couple beautifully recreate their wedding day</a></strong></em></span></p> <p><span style="text-decoration: underline;"><em><strong><a href="/health/caring/2015/12/couple-with-dementia-relives-night-they-met/">Couple with dementia relives night they met in tear-jerking video</a></strong></em></span></p>

Caring