Matthew Perry's cause of death finally revealed
The sudden and tragic death of Friends actor Matthew Perry shocked fans worldwide. Now the County of Los Angeles' medical examiner has finally released its report detailing the cause of his demise, attributing it to the acute effects of ketamine.
Perry, best known for his role as Chandler Bing in the iconic TV series, passed away at the age of 54 on the morning of October 28, after a game of pickleball. He returned home and sent his assistant on an errand. Two hours later, the assistant returned to find Perry unresponsive in the spa. Emergency services were called, but paramedics pronounced Perry dead at the scene.
At the time, the coroner's report listed only drowning, coronary artery disease and the effects of opioid buprenorphine as contributing factors, ultimately ruling the death as an accident.
Ketamine, a dissociative anaesthetic with hallucinogenic effects, has now been determined to have played a significant role in Perry's demise. The autopsy revealed that Perry was undergoing ketamine infusion therapy to manage depression and anxiety. However, the ketamine found in his system at the time of death could not be attributed to the most recent therapy session, as its half-life is only three to four hours. The report stated that the high levels of ketamine in his postmortem blood could lead to cardiovascular overstimulation and respiratory depression.
Perry had a history of substance abuse, openly discussing his battles with addiction dating back to his time on Friends in the 1990s. Despite being reportedly clean for 19 months before his death, the toxicology report revealed ongoing ketamine infusions. Perry had detailed his experiences with ketamine in his memoir, describing it as a "giant exhale" that made him feel as though he were "dying".
“Ketamine was a very popular street drug in the 1980s," Perry wrote in his book Friends, Lovers and the Big Terrible Thing. "There is a synthetic form of it now, and it’s used for two reasons: to ease pain and help with depression. Has my name written all over it – they might as well have called it ‘Matty’.”
During the pandemic, Perry received ketamine infusions in a Swiss rehab clinic, as revealed in his memoir. He explained that the drug, known for its pain-relieving and antidepressant properties, provided a unique and different experience. However, he also acknowledged the rough hangover associated with ketamine, ultimately stating that the drug was not for him.
“Taking K is like being hit in the head with a giant happy shovel," he wrote. "But the hangover was rough and outweighed the shovel. Ketamine was not for me.”
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